Gene network reconstruction from transcriptional dynamics under kinetic model uncertainty

A case for the second derivative

Open access publication

D. R. Bickel, Z. Montazeri, P.-C. Hsieh, M. Beatty, S. J. Lawit, and N. J. Bate, “Gene network reconstruction from transcriptional dynamics under kinetic model uncertainty: A case for the second derivative,” Bioinformatics 25, 772-779 (2009).

Supplementary files

Supplementary text (PDF) | Supplementary spreadsheet

Data

Gene expression time course data with replication

Software

Dynomics is the software suite created at the University of Ottawa that implements the gene network reconstruction methods of the above paper. The source code of Dynomics has been available for download as a zip archive file from this web page since 17 February 2009. Dynomics is compatible with Windows, UNIX, Linux, and Macintosh operating systems. It requires a recent installation of R.

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